Dermatological Composition of Deodorants and Potential Cutaneous Risks: A Narrative Review and Clinical Implications

This narrative review examines the dermatological composition of deodorants and antiperspirants, highlighting potential cutaneous risks associated with their use. It identifies fragrances, including natural ones, and isothiazolinone preservatives as primary causes of skin sensitization. Additionally, vehicles and surfactants like propylene glycol and alkyl glucosides may contribute to irritation, especially under occlusive conditions. While aluminum salts effectively reduce sweat flow, they can cause local adverse effects, which can be minimized with proper application techniques. Magnesium hydroxide emerges as a promising alternative for odor control, offering favorable skin tolerability by neutralizing odor compounds and modulating pH without blocking sweat ducts. The review concludes that selecting formulations with lower allergenic potential and providing proper usage guidance are crucial for minimizing adverse skin outcomes while maintaining effective odor control.