Delayed Treatment Leading to Multisystem Complications in a Child with Systemic Lupus Erythematosus

August 2025 in “ Romanian Journal of Rheumatology ”

Ayesha Nabeela Liyakath Ali, J. U. Senthamizhan, Elayaraja Sivaprakasam, Sarala Premkumar, Latha Ravichandran, Barathi Gunabooshanam, Mahesh Janarthanan

alopecia systemic lupus erythematosus steroids IVIG rituximab hair loss intravenous immunoglobulin

A 16-year-old female with systemic lupus erythematosus (SLE) experienced severe multisystem complications due to a 2-year delay in diagnosis, during which she used herbal medications and acupuncture. Her symptoms included joint pain, fevers, alopecia, oral ulcers, seizures, and more. Upon diagnosis, she received treatment with steroids, IVIG, and rituximab, resulting in gradual improvement. The case highlights that delayed diagnosis in SLE can lead to increased disease activity and organ damage, emphasizing the importance of early diagnosis and management for better outcomes.

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