A Delayed Onset Cyst-Like Lesion at the Lip After Hyaluronic Acid Filler Injection: A Case Report

May 2025 in “ Oral Sciences Reports ”

Atapol Yongvikul, Manop Khanijou, Natthamet Wongsirichat, Thongnard Kumchai

hyaluronic acid filler injection lip nodule cyst-like lesion salivary gland cyst soft tissue tumor lip filler lip injection

TLDR A lip nodule from a filler injection was successfully removed with surgery.

A 45-year-old female experienced a delayed complication from a hyaluronic acid filler injection in the lower lip, developing a painless, well-defined nodule four weeks post-procedure. The nodule, resembling a cyst-like lesion, was successfully treated with surgical excision. This case highlights the importance for clinicians to consider various potential causes for lip nodules, including salivary gland cysts, soft tissue tumors, and filler-related nodules, as they present unique diagnostic and management challenges.

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