Decoding Pumpkin Seeds for Hair Loss: A Computational Perspective

July 2023 in “ Zenodo (CERN European Organization for Nuclear Research) ”

Kashif Abbas, Mudassir Alam, Tanjeem Raza, S Mohd. Hasan Abedi

pumpkin seed compounds androgenetic alopecia 5-alpha-reductase testosterone dihydrotestosterone DHT ADME/T analysis AGA

TLDR Pumpkin seeds may help treat hair loss by blocking a key enzyme.

This study explores the potential of pumpkin seed compounds in treating androgenetic alopecia (AGA) by targeting the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT), a key factor in hair loss. Through virtual simulations and ADME/T analysis, the research evaluates the interactions between pumpkin seed compounds and the enzyme, aiming to provide insights into their effectiveness as a natural therapeutic option for AGA.

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