TLDR Cyclosporine can cause a unique skin condition called "cyclosporine-induced folliculodystrophy."
A 34-year-old kidney transplant patient developed a unique skin condition due to cyclosporine, characterized by flesh-colored, follicular papules on the face, trunk, and extremities. This case, along with 2 previous reports, suggested that immunosuppressive doses of cyclosporine were the cause. The authors detailed the clinical and histologic findings and proposed the term "cyclosporine-induced folliculodystrophy" (CIF) for this condition. They also introduced a theory based on recent in vitro studies to explain the pathogenic events and established 3 clinical and 4 histopathologic criteria for diagnosing CIF.
45 citations
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September 2001 in “Journal of Investigative Dermatology” Cyclosporin A promotes hair cell growth and affects protein kinase C levels.
54 citations
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February 1994 in “Journal of Investigative Dermatology”
36 citations
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January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
40 citations
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August 2010 in “Archives of dermatology” A 5-year-old boy's skin condition improved with systemic valganciclovir after a cardiac transplant and immunosuppressive therapy.
12 citations
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November 2014 in “Journal of Cutaneous Medicine and Surgery” Antiviral medication valganciclovir may improve skin and hair in Trichodysplasia Spinulosa patients.
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March 2005 in “Journal of the American Academy of Dermatology” Follicular dystrophy in immunocompromised patients may be linked to medication or viral factors and can improve with treatment changes.
41 citations
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December 2008 in “Journal of the American Academy of Dermatology” Oral valganciclovir improved a patient's skin condition caused by immunosuppression.
