TLDR Cyclosporine can cause a unique skin condition called "cyclosporine-induced folliculodystrophy."
A 34-year-old kidney transplant patient developed a unique skin condition due to cyclosporine, characterized by flesh-colored, follicular papules on the face, trunk, and extremities. This case, along with 2 previous reports, suggested that immunosuppressive doses of cyclosporine were the cause. The authors detailed the clinical and histologic findings and proposed the term "cyclosporine-induced folliculodystrophy" (CIF) for this condition. They also introduced a theory based on recent in vitro studies to explain the pathogenic events and established 3 clinical and 4 histopathologic criteria for diagnosing CIF.
45 citations,
September 2001 in “Journal of Investigative Dermatology” Cyclosporin A promotes hair cell growth and affects protein kinase C levels.
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36 citations,
January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
40 citations,
August 2010 in “Archives of dermatology” A 5-year-old boy's skin condition improved with systemic valganciclovir after a cardiac transplant and immunosuppressive therapy.
12 citations,
November 2014 in “Journal of Cutaneous Medicine and Surgery” Antiviral medication valganciclovir may improve skin and hair in Trichodysplasia Spinulosa patients.
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41 citations,
December 2008 in “Journal of the American Academy of Dermatology” Oral valganciclovir improved a patient's skin condition caused by immunosuppression.
9 citations,
January 2015 in “Fundamental & clinical pharmacology” Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
