Cyclosporine-Induced Folliculodystrophy
January 2004
in “
Journal of the American Academy of Dermatology
”
Studysummary This case report describes a 34-year-old kidney transplant patient who developed a unique skin condition linked to cyclosporine, characterized by flesh-colored papules, and introduces "cyclosporine induced folliculodystrophy" as a term for this condition.
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A 34-year-old kidney transplant patient developed a unique skin condition due to cyclosporine, characterized by flesh-colored, follicular papules on the face, trunk, and extremities. This case, along with 2 previous reports, suggested that immunosuppressive doses of cyclosporine were the cause. The authors detailed the clinical and histologic findings and proposed the term "cyclosporine-induced folliculodystrophy" (CIF) for this condition. They also introduced a theory based on recent in vitro studies to explain the pathogenic events and established 3 clinical and 4 histopathologic criteria for diagnosing CIF.
