Cutaneous Lesions and Clinical Outcomes in Five Cats After Frunevetmab Injections

    Anjie Storrer, John T. Mackie, Marcus Gunew, Jeylan Aslan
    Studysummary This case series reports on five cats who experienced moderate to severe skin reactions after receiving the frunevetmab injection, noting pruritus, alopecia, and ulcerations developing within days of treatment.
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    This case series investigates cutaneous adverse events in five cats following frunevetmab injections, a treatment for osteoarthritis pain. All cats developed moderate to severe pruritus, leading to self-inflicted trauma and resulting in dermatitis, alopecia, and ulcerations, with symptoms appearing 3 to 18 days post-injection. One cat required surgical resection for persistent ulcerative lesions. The study suggests these reactions may be linked to neuropathic itch, akin to feline idiopathic ulcerative dermatitis. Despite these adverse effects, frunevetmab is still recommended by veterinarians, with a need for further research to understand and manage these reactions better.
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