TLDR A method was developed to grow hair follicles in a lab for research on hair growth and health.
The study from 1988 focused on developing a culture system for hair follicles to facilitate research on cellular differentiation, gene expression, and the effects of various factors on hair growth. The researchers aimed to maintain hair follicles as three-dimensional structures using a collagen matrix, which allowed for prolonged analysis. This system was intended to enable the transfection of hair cells with keratin genes and to study the impact of nutritional factors, hormones, drugs, and carcinogens on hair growth and epithelial neoplasms. The success of the culture system was measured by the continued synthesis of hair-specific proteins.
87 citations
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October 1987 in “Journal of Investigative Dermatology” 7 citations
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February 1982 in “Australian Journal of Biological Sciences” Epithelial cells from young rat hair follicles grow and form aggregates in culture, but don't produce hair keratin proteins.
88 citations
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January 1981 in “British Journal of Dermatology” A new method helps grow human hair cells using a cow eye lens.
44 citations
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
5 citations
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April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
67 citations
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December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
51 citations
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May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.