COVID and Cancer: A Complete 3D Advanced Radiological CT-Based Analysis to Predict the Outcome

    January 2023 in “ Cancers ”
    Syed Rahmanuddin, Asma Jamil, Ammar Chaudhry, Tyler Seto, Jordyn Brase, Pejman Motarjem, Marjaan Khan, Cristian Tomasetti, Umme Farwa, William D. Boswell, Haris Ali, Danielle Guidaben, Rafay Haseeb, Guibo Luo, Guido Marcucci, Steven T. Rosen, Wenli Cai
    The study analyzed CT scans of 22 cancer patients with confirmed COVID-19 infection, revealing significant lung damage, including a >50% decrease in lung volume and increased density due to scar formation. It highlights the high risk of severe COVID-19 outcomes in cancer patients, especially those with hematologic malignancies like leukemia, due to their weakened immune systems. The study emphasizes the importance of CT-based radiomics for precise diagnosis and management, suggesting frequent follow-ups with labs and low-dose CT scans to monitor lung damage, despite the lack of a standardized protocol. Limitations include a small sample size and lack of comparison with non-cancer patients.
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