Concordance Among In-Vivo Reflectance Confocal Microscopy, Trichoscopy, and Histopathology in the Evaluation of Alopecia Areata Incognita

    October 2024 in “ Dermatology Practical & Conceptual ”
    Michela Starace, Nathalie De Carvalho, Daniel Fernandes Melo, Stephano Cedirian, Victor Desmond Mandel, Carla Jorge Machado, Cosimo Misciali, Giovanni Pellacani, Bianca Maria Piraccini, Marco Ardigò
    TLDR Reflectance confocal microscopy is a promising non-invasive tool for diagnosing alopecia areata incognita.
    The study highlights the potential of reflectance confocal microscopy (RCM) as a non-invasive diagnostic tool for alopecia areata incognita, showing substantial agreement with histopathology in identifying key features. Although some discrepancies were noted, particularly in detecting inflammatory infiltrates, RCM's non-invasive nature could enhance patient experiences and allow for real-time disease monitoring, leading to improved treatment decisions. The technology's applicability may extend beyond alopecia areata incognita, offering more patient-friendly diagnostic options in the field of trichology.
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