Complications Of Androgenetic Alopecia Treatments: Systematic Review And Meta-Analysis

    December 2025 in “ Revista fisio&terapia. ”
    Nuno Manuel Monteiro Domingues, Susana Margarida Pires da Silva
    Image of study
    TLDR Androgenetic alopecia treatments slightly increase the risk of side effects, especially sexual dysfunction and skin reactions.
    This systematic review and meta-analysis evaluated complications and adverse events associated with androgenetic alopecia (AGA) treatments lasting 3 months or more, analyzing data from 6 studies with 5,725 participants. The study found that AGA treatments are linked to a small increased risk of adverse events, with dutasteride showing the highest risk (OR 2.10). Finasteride and minoxidil also showed increased risks (OR 1.87 and OR 1.35, respectively). The main adverse events identified were sexual dysfunction for finasteride and dutasteride, and local dermatologic reactions for minoxidil. The study recommends clinical monitoring and informed discussions with patients about these risks.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community 1 month of using fin, so happy

      in Progress Pictures  862 upvotes 1 year ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

      community Any growth (been taking iron supplements)

      in Is this regrowth? 4 months ago
      The conversation discusses hair loss treatments, focusing on iron supplements for low ferritin levels and considering finasteride and minoxidil if thinning persists. There is debate over starting with finasteride versus dutasteride, with some users advocating for dutasteride due to its potency, while others caution about potential side effects.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Hair loss treatment tier list by Dr Oscar Muñoz

      in Treatment  927 upvotes 1 year ago
      Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

    Similar Research

    6 / 1000+ results