Efficacy and Safety of ENERGI-F701 Solution Versus 2% Minoxidil Solution for Female Pattern Hair Loss: A Phase II, Multi-Center, Randomized, Double-Blind, Head-to-Head, Parallel Trial

April 2023 in “ Journal of Investigative Dermatology ”

S. Ma, Y. Wei, M. Wu, H. Tsai, D. Lee, Y. Chang, C. Chen

ENERGI-F701 minoxidil female pattern hair loss hair density hair shedding local skin reactions hair thickness investigator photographic assessment questionnaire female hair loss quality of life questionnaire Regaine FPHL

TLDR ENERGI-F701 solution was found to be more effective and safer than Regaine® 2% minoxidil solution in treating female pattern hair loss, with increased hair density and less side effects.

In this study, researchers compared the efficacy and safety of ENERGI-F701 solution to Regaine® 2% minoxidil solution for treating female pattern hair loss (FPHL). The study included 67 women with FPHL who were randomly assigned to either the ENERGI-F701 or Regaine® group. The results showed that both groups significantly increased hair density at week 12. The ENERGI-F701 group also had a significant reduction in all-day shed hair count at weeks 4 and 6, as well as a lower percentage of local skin reactions compared to the Regaine® group. Additionally, the ENERGI-F701 group had greater increases in hair density and thickness, as well as better scores on the investigator photographic assessment questionnaire and the female hair loss quality of life questionnaire. Overall, the ENERGI-F701 solution was found to be effective in treating FPHL without initial hair shedding compared to the Regaine® 2% minoxidil solution.

View this study on jidonline.org →

Discuss this study in the Community →

Related Research

6 / 6 results

research Randomized Clinical Trial of Low-Dose Oral Minoxidil for the Treatment of Female Pattern Hair Loss: 0.25 mg Versus 1 mg

3 citations, January 2022 in “Journal of The American Academy of Dermatology”

1 mg/day of low-dose oral minoxidil is effective and safe for treating female hair loss.

research Faculty Opinions Recommendation of Sublingual Minoxidil for the Treatment of Male and Female Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase 1B Clinical Trial

September 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study

research Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study

2 citations, October 2020 in “Dermatologic Therapy”

Herbal solution improves hair diameter and density more than 5% minoxidil for androgenetic alopecia.

Efficacy and Safety of Topical Combination of 3% Minoxidil and 0.25% Finasteride Versus 3% Minoxidil Solution in Female-Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy and Safety of Topical Combination of 3% Minoxidil and 0.25% Finasteride Versus 3% Minoxidil Solution in Female-Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

1 citations, August 2018 in “Journal of The American Academy of Dermatology”

Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.

research Androgenetic Alopecia in the Female

82 citations, March 1994 in “Archives of Dermatology”

2% topical minoxidil effectively treats female hair loss with minimal side effects.

research Quantitative Estimation of Hair Growth: Androgenetic Alopecia in Women and the Effect of Minoxidil

85 citations, December 1990 in “Journal of Investigative Dermatology”

Minoxidil promotes hair growth in women with early-stage alopecia.

Efficacy and Safety of ENERGI-F701 Solution Versus 2% Minoxidil Solution for Female Pattern Hair Loss: A Phase II, Multi-Center, Randomized, Double-Blind, Head-to-Head, Parallel Trial

Related Community Posts Join

community C’est terrible - at my wits end

community Is there a point in using tretinoin and microneedling if I take oral minoxidil? Should I quit drinking energy drinks on Oral Minoxidil?

community Have you noticed any difference in mood or energy since being on fin/dut?

community Feeling energyless and think my 2.5mg dut per day might be causing it

community Red light therapy - research says they work, reviews say they don't - Turns out commercial device are severely under-powered, so could this actually work?

community Take multivitamins if you have sexual side effects! it's amazing