Combined Therapy in the Topical Treatment of Androgenetic Alopecia: Integrative Review on Minoxidil, Finasteride, Growth Factors, and the Scientific Foundations of the Vittahair Protocol

    November 2025
    Lais Serezini Oliveira Abdalla, Jackeline de Souza Alecrim, Mariane Parma Ferreira de Souza
    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

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    Studysummary This study reviews existing literature on regenerative therapy for androgenetic alopecia, highlighting that integrating growth factors, biotin, D-pantenol, and other active ingredients using the Vittahair protocol may enhance hair follicle regeneration, increase hair density, and improve hair quality, providing a precise and evidence-based treatment alternative. Our plain-language summary of this paper — not a Tressless recommendation.
    The document provides an integrative review of combined topical therapy for androgenetic alopecia, focusing on minoxidil, finasteride, growth factors, and the scientific basis of the Vittahair protocol. It discusses the efficacy of these treatments in promoting hair growth and reducing hair loss. The review highlights that combining these agents can enhance therapeutic outcomes due to their complementary mechanisms of action. Minoxidil is noted for its vasodilatory effects, finasteride for its role in inhibiting dihydrotestosterone, and growth factors for stimulating hair follicle activity. The Vittahair protocol is presented as a scientifically grounded approach that leverages these combined effects to optimize treatment efficacy for patients with androgenetic alopecia.
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