A Review of the Characteristics of Clinical Trials and Potential Medications for Alcohol Dependence: Data Analysis from ClinicalTrials.gov

June 2023 in “ Medicina ”

Fahad S. Alshehri

Studysummary This study provides a detailed overview of 1,295 clinical trials related to alcohol dependence registered on ClinicalTrials.gov, highlighting that 59.15% of these trials have been completed, primarily as interventional studies, with most located in North America.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This systematic review analyzed 1,295 clinical trials on alcohol dependence from ClinicalTrials.gov, with 766 completed and 230 recruiting. Most trials were interventional (88.41%) and conducted in North America (67.64%). The review highlights the need for more effective pharmacological treatments, as none of the trials had been approved for marketing. Naltrexone, Topiramate, and Acamprosate were the most studied drugs, with Naltrexone being the most frequently researched. The study emphasizes the need for more resources and comprehensive studies to address alcohol dependence, a significant global health issue.

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