Chemotropic Neomorphogenesis of Hemodynamically Active Hypervascular Patterns in Hare Skin by a Monocytic Polypeptide Mediator for Blood Vessel Growth (Monocyto-Angiotropin) Promotes Tissue Hyperfunction (Hair Growth)

    January 1985 in “ Protides of the biological fluids ”
    Michael Höckel, Wilfried Wagner, H.W. Renner, Josef H. Wissler
    TLDR Injecting monocyto-angiotropin into hare skin increases hair growth by forming new blood vessels.
    The study demonstrated that injecting monocyto-angiotropin (MAT), a low molecular weight polypeptide from porcine monocytes, into the skin of hares induced new blood vessel formation and active hemodynamics, leading to significant hair growth at the injection site within 7-10 days. This effect was not observed in control sites, which took over 5 weeks to show comparable hair growth. The findings suggested that MAT could promote tissue hyperfunction and might have implications for wound healing and tumor growth.
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