Research Landscapes And Knowledge Structure Of Cardiac Xenotransplantation: A Bibliometric Analysis
March 2026
in “
Cell Transplantation
”
Studysummary In this study, a bibliometric and science-mapping analysis revealed that cardiac xenotransplantation research is expanding rapidly, with significant collaboration primarily among institutions in the United States, Europe, and East Asia, and a focus on gene-edited donors and clinical trial readiness.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Cardiac xenotransplantation research is progressing from basic research to early clinical use, with a steady growth in publications, particularly in recent years. The field is characterized by strong collaboration among institutions in the United States, Europe, and East Asia, with a few authors and centers contributing significantly to the literature. Research topics primarily focus on rejection, complement biology, gene-edited donors, biosafety, clinical trial readiness, and pig-to-human models. The findings suggest that the field is maturing towards clinical implementation, providing insights for guiding research priorities, funding, and policy planning.
