Research Landscapes And Knowledge Structure Of Cardiac Xenotransplantation: A Bibliometric Analysis

Cardiac xenotransplantation research is progressing from basic research to early clinical use, with a steady growth in publications, particularly in recent years. The field is characterized by strong collaboration among institutions in the United States, Europe, and East Asia, with a few authors and centers contributing significantly to the literature. Research topics primarily focus on rejection, complement biology, gene-edited donors, biosafety, clinical trial readiness, and pig-to-human models. The findings suggest that the field is maturing towards clinical implementation, providing insights for guiding research priorities, funding, and policy planning.