Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy

The document reviewed how recent advances in live imaging techniques, such as live cell imaging and intravital microscopy, provided new insights into stem cell behavior and dynamics in their native environments. These techniques revealed that stem cells were more dynamic than previously thought, with the ability to gain or lose their "stemness" over time. This challenged earlier static observations and suggested a model of stem cell plasticity during development, homeostasis, regeneration, and tumor formation.