Steroids Excreted by Human Skin: C19-Steroids in Axillary Hair

January 1983 in “ PubMed ”

Tóth I, Faredin I

androgen steroids C19-steroid sulphates 4-androstene-3 beta, 17 beta-diol testosterone dehydroepiandrosterone sulphate sebaceous glands sweat glands DHEA sulphate

TLDR Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.

The study conducted by I Tóth et al. in 1983 focused on the isolation and determination of seven free androgen steroids and four C19-steroid sulphates from the axillary hair of sexually mature healthy males and females. It was found that in 1 g of axillary hair, free steroids such as 4-androstene-3 beta, 17 beta-diol, testosterone, and others were present in nanomol amounts, while sulphate steroids like dehydroepiandrosterone sulphate were found in approximately 1000 times these amounts. The study suggested that free steroids in hair were products of sebaceous glands, whereas sulphate ester steroids were products of sweat glands.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 3 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 2 years ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 169 upvotes 1 year ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?

in Finasteride/Dutasteride 31 upvotes 1 year ago

Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 2 years ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

Related Research

1 / 1 results

research Steroids Excreted by Human Skin: C19-Steroids in Axillary Hair

5 citations , January 1983 in “PubMed”

Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.