Botulinum Toxin A in the Treatment of Facial Reflex Sympathetic Dystrophy: A Case Report

In a study conducted 10 years ago, 50 male subjects aged between 19 and 57 years with Norwood/Hamilton ratings of II to IV were treated with peripheral scalp injections of botulinum toxin-A (BTX-A) to determine its effect on hair loss and hair growth. The study lasted 60 weeks and involved two 24-week treatment cycles. The results showed a statistically significant increase in hair count of 18% between baseline and week 48, similar to results reported with Propecia®. Hair loss was reduced by 39%. The study concluded that strategically placed BTX-A injections could modify scalp physiology, resulting in reduced hair loss and new hair growth in some men with androgenetic alopecia.