Bioactive glass 1393 promotes angiogenesis and accelerates wound healing through ROS/P53/MMP9 signaling pathway

Bioactive glass 1393 has been shown to accelerate wound healing by promoting angiogenesis through the ROS/P53/MMP9 signaling pathway. The study demonstrated that bioactive glass 1393 enhances the formation of granulation tissue, collagen deposition, and angiogenesis. It achieves this by up-regulating angiogenesis-related factors and inhibiting ROS and P53 expression. The research included both <i>in vivo</i> and <i>in vitro</i> studies, confirming the pro-angiogenic effects of bioactive glass 1393 and its potential in wound healing applications.