A Bibliometric Analysis of Endoplasmic Reticulum Stress and Atherosclerosis

This bibliometric analysis examines 1,035 publications on the relationship between endoplasmic reticulum stress (ERS) and atherosclerosis (AS) from 2000 to 2023, highlighting the significant role of ERS in AS development. The study identifies key research areas such as endothelial dysfunction, inflammation, and apoptosis, with China and the United States leading in publication output. Prominent contributors include Ira Tabas and Columbia University. The analysis underscores the potential of targeting ERS for therapeutic interventions in AS, with emerging research focusing on vascular calcification and heart failure. It emphasizes the need for further research on biological targets to modulate ER function and the translation of basic research into clinical applications.