TLDR Baricitinib is effective and safe for treating severe alopecia areata.
This retrospective analysis evaluated the efficacy and safety of baricitinib in 30 patients with severe alopecia areata. The study found that hair regrowth began on average after 4 months, with complete regrowth in 16 patients after 10 months. By the 12th month, 63% of patients achieved a SALT score of ≤20, indicating significant improvement. Adverse events were mostly mild, including laboratory abnormalities, headache, and mild infections, leading to treatment discontinuation in only one case. The findings support baricitinib as an effective and safe treatment for severe alopecia areata.
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September 2023 in “Dermatology and Therapy” Baricitinib helps improve hair growth in severe alopecia, with better results in less severe cases and higher doses working faster.
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January 2023 in “Przegląd Dermatologiczny” The Polish Society of Dermatology recommends treatments for alopecia areata that vary by severity, including topical and systemic medications, with long-term maintenance important for management.
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June 2023 in “Frontiers in immunology” JAK inhibitors help hair regrowth in alopecia areata but have a high risk of side effects.
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June 2023 in “Indian journal of dermatology, venereology, and leprology” Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.
July 2023 in “IntechOpen eBooks” New treatments for alopecia areata show promise, but more research is needed to confirm their effectiveness.
September 2024 in “Journal of the European Academy of Dermatology and Venereology” Baricitinib effectively reduces hair loss in severe alopecia areata with mild side effects.
