Symptoms of ASIA Syndrome in a Female Patient with Tattoos: A Case Report

    November 2025 in “ Clinical Cosmetic and Investigational Dermatology ”
    Monika J. Leżanko, Błażej A. Pilch, Marta Kasprowicz‐Furmańczyk, Agnieszka Owczarczyk‐Saczonek
    This case report discusses a 46-year-old female patient with multiple colored tattoos who developed symptoms consistent with autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA), including musculoskeletal, neurological, and cutaneous manifestations. The patient had a medical history of hypothyroidism and vulvar lichen sclerosus. The report highlights the importance of distinguishing ASIA syndrome from other immune-mediated diseases and calls for careful clinical evaluation, including a thorough review of the patient's medical history and potential exposure to immunostimulatory substances.
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