An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review.
August 2018
in “PubMed”
TLDR An 8-year-old with severe hair loss regrew all hair after six months of tofacitinib treatment.
In 2018, a case study was conducted on an 8-year-old male patient suffering from alopecia universalis, a condition characterized by complete hair loss. The patient was initially treated with Clobetasol 0.05% solution and Kenalog 2.5 mg/ml injections, but his condition worsened. The patient, his mother, and the clinician then agreed to try tofacitinib 5 mg twice daily along with continued usage of topical steroids. After three months of treatment, the patient showed complete regrowth of eyebrows and minimal hair growth on the posterior occiput. By the six-month mark, the patient had 100% regrowth of eyebrows and complete scalp regrowth, resulting in a Severity of Alopecia Tool (SALT) score of 0. The patient reported mild headaches as a side effect after six months, leading to discontinuation of treatment. This case study marked the youngest patient ever reported to be successfully treated with oral tofacitinib 5 mg twice daily for alopecia and its variants.
View this study on pubmed.ncbi.nlm.nih.gov →
Related
research Hair and Nail Conditions: Alopecia Evaluation.
Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.
research Hair Loss in Lichen Planopilaris and Frontal Fibrosing Alopecia: Not Always Irreversible
Hair loss from conditions like LPP and FFA can potentially be reversed with the right treatment.
research An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review.
An 8-year-old with severe hair loss regrew all hair after six months of tofacitinib treatment.
research Hair disorders
The document's conclusion cannot be provided because the document cannot be parsed.
research Topical and intralesional therapies for alopecia areata
No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
research Hair Diseases (Alopecia Areata and Androgenetic Alopecia)
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.