Alopecia Areata After Hepatitis C Virus Infection Treatment: A Case Report

April 2021 in “ Anatolian current medical journal : ”

Esma Eroğlu

alopecia areata interferon-free direct-acting antiviral therapy sofosbuvir ribavirin chronic hepatitis C virus infection DAA therapy SOF/RBV HCV

TLDR A patient developed hair loss after hepatitis C treatment with sofosbuvir and ribavirin.

A case report from April 2021 described a rare instance of alopecia areata developing in a patient following treatment with the interferon-free direct-acting antiviral (DAA) therapy combination of sofosbuvir and ribavirin (SOF/RBV) for chronic hepatitis C virus (HCV) infection. Despite the generally low side effects associated with DAA therapies, this case highlighted alopecia areata as a potential, though uncommon, complication.

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research Lichen Planus and Other Cutaneous Manifestations in Chronic Hepatitis C: Pre- and Post-Interferon-Based Treatment Prevalence in a Cohort from a Low Hepatitis C Virus Endemic Area

34 citations , May 2008 in “Journal of the European Academy of Dermatology and Venereology”

Skin problems like itching, dry skin, and hair loss are more common in hepatitis C patients after interferon treatment, but lichen planus is not linked to the infection.

research Reversible Alopecia Universalis Secondary to PEG-Interferon Alpha-2b and Ribavirin Combination Therapy in a Patient with Chronic Hepatitis C Virus Infection

41 citations , September 2007 in “European Journal of Gastroenterology & Hepatology”

A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.

research Reversible Alopecia Universalis During Treatment with PEG-Interferon and Ribavirin for Chronic Hepatitis C

27 citations , April 2005 in “Journal of Chemotherapy”

Some patients may experience temporary total hair loss from hepatitis C treatment with PEG-interferon and ribavirin.