TLDR Patients with alopecia areata should be checked for muscle spasms, diarrhea, and ANA to avoid missing Satoyoshi syndrome.
Satoyoshi syndrome, an autoimmune disorder affecting mainly girls and young women, was characterized by alopecia, muscle spasms, and diarrhea, with 60% of patients showing antinuclear antibodies (ANA). Trichoscopy revealed yellow dots similar to alopecia areata, leading to potential misdiagnosis. The study proposed diagnostic criteria and identified two subtypes: ANA-positive, which responded well to glucocorticosteroids, and ANA-negative, with a poorer prognosis. It recommended that patients with alopecia areata, especially alopecia totalis, be evaluated for muscle spasms, diarrhea, and ANA to avoid missing Satoyoshi syndrome.
43 citations,
August 2013 in “Pediatric Dermatology” Trichoscopy is good for diagnosing and monitoring hair and scalp problems in children but needs more research for certain conditions.
6 citations,
May 2012 in “Pediatric Dermatology” Satoyoshi syndrome can cause hair loss and other serious health issues, and is hard to diagnose.
141 citations,
March 2011 in “Journal of Dermatology” Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.
89 citations,
December 2010 in “The Journal of Dermatology” The conclusion is that an algorithm using trichoscopy helps diagnose different types of hair loss but may need updates and a biopsy if results are unclear.
18 citations,
February 2006 in “Brain & development” A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.
13 citations,
October 2003 in “Clinical pediatrics” Steroid treatment greatly improved the symptoms of a boy with a rare disorder called Satoyoshi syndrome.
12 citations,
October 2001 in “Pediatric Dermatology” Satoyoshi syndrome symptoms can improve with corticosteroids and surgery.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.
