Alopecia and cardiovascular events

    December 2000 in “ The Lancet
    A Kasperlik-Załuska, Malgorzata Godziejewska
    TLDR Early male hair loss might signal higher heart disease risk.
    The document discussed the potential link between early androgenetic alopecia in men and serious cardiovascular events, suggesting that this type of hair loss might be a marker of metabolic disorders such as insulin resistance, hyperinsulinaemia, obesity, hypertension, and dyslipidaemia. These conditions were considered analogous to polycystic ovary syndrome (PCOS) in women, where similar metabolic issues are present. The authors proposed that androgenetic alopecia could be related to the same underlying disorder as hirsutism in women with PCOS, and that these metabolic disorders might increase the risk of mortality from cardiovascular events. They recommended genetic investigations in families of women with PCOS and men with androgenetic alopecia to further explore this connection.
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