Adult Onset Still Disease: A Case Study

    May 2021 in “ Medicina internă ”
    Vlad Pînzariu, Alexandra Jichitu, Laura Manea, A Mihail, Daniela Grozvau, Laura Tribus
    TLDR High-dose corticosteroid treatment helped improve symptoms in a patient with Adult Onset Still Disease.
    Three years ago, a 31-year-old male with a history of alopecia areata was diagnosed with Adult Onset Still Disease (AOSD), a systemic inflammatory disease of unknown cause. The patient presented with symptoms such as high fever, sore throat, and diffuse myalgia. Despite various treatments including anti-inflammatory, antithermic, antibiotic, and corticosteroid, the patient remained symptomatic. However, pulse-therapy with Methylprednisolone resulted in fever remission for more than 72 hours. Two months after the initiation of corticosteroid therapy, the patient's symptoms greatly diminished, although alopecia areata was still partially present. The diagnosis of AOSD was challenging due to its unspecific clinical presentation and the fact that it is a diagnosis of exclusion.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 8 months ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community 17M biotin and minoxidil hair regrowth progress

      in Progress Pictures  83 upvotes 1 year ago
      A user's hair regrowth journey using biotin and minoxidil after initial treatments with Nizoral shampoo and Ketoconazole serum didn't work. The comments suggest the hair loss might not be male pattern baldness (MPB), but possibly Alopecia Areata, an autoimmune disorder, and recommend getting a second opinion and considering other treatments like corticosteroids.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I’ve read multiple times that Fin increases hair quality… NOT for me!

      in Treatment  97 upvotes 1 year ago
      A user has been on finasteride for 6 months and feels their hair quality has worsened, experiencing more hair loss and scalp irritation. They are considering seeing a dermatologist, while others suggest the issue might be unrelated to finasteride, possibly due to deficiencies or other conditions.

    Similar Research

    5 / 1000+ results