Adult Onset Still Disease: A Case Study

    May 2021 in “ Medicina internă ”
    Vlad Pînzariu, Alexandra Jichitu, Laura Manea, A Mihail, Daniela Grozvau, Laura Tribus
    TLDR High-dose corticosteroid treatment helped improve symptoms in a patient with Adult Onset Still Disease.
    Three years ago, a 31-year-old male with a history of alopecia areata was diagnosed with Adult Onset Still Disease (AOSD), a systemic inflammatory disease of unknown cause. The patient presented with symptoms such as high fever, sore throat, and diffuse myalgia. Despite various treatments including anti-inflammatory, antithermic, antibiotic, and corticosteroid, the patient remained symptomatic. However, pulse-therapy with Methylprednisolone resulted in fever remission for more than 72 hours. Two months after the initiation of corticosteroid therapy, the patient's symptoms greatly diminished, although alopecia areata was still partially present. The diagnosis of AOSD was challenging due to its unspecific clinical presentation and the fact that it is a diagnosis of exclusion.
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