Acquired Ichthyosis, Alopecia, and Loss of Hair Pigment Associated with Leiomyosarcoma

    A Farrell
    Studysummary This study reported that acquired ichthyosis and hair changes in a 70-year-old woman with leiomyosarcoma resolved after the surgical removal of the tumor. Our plain-language summary of this paper — not a Tressless recommendation.
    The document reports the case of a 70-year-old woman with acquired ichthyosis and leiomyosarcoma, a less common malignancy associated with this condition. She also exhibited unusual symptoms of generalized thinning and loss of hair pigment. A scalp biopsy confirmed the presence of ichthyosis. After the tumor was surgically removed, the ichthyosis resolved, and her hair began to regrow with darker pigment. This case highlights the potential association between acquired ichthyosis and internal malignancies, and the possible resolution of symptoms following successful treatment of the underlying malignancy.
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