Acquired Ichthyosis, Alopecia, and Loss of Hair Pigment Associated with Leiomyosarcoma

The document described a case of a 70-year-old woman with acquired ichthyosis and leiomyosarcoma, a rare type of cancer. She also experienced generalized thinning and loss of pigment in her hair. A scalp biopsy confirmed the presence of ichthyosis. Remarkably, after the surgical removal of the tumor, her ichthyosis resolved, and her hair regrew with a darker color. This case highlighted the association between acquired ichthyosis and internal malignancies, including less common ones like leiomyosarcoma.