A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome

    January 2004 in “The Journal of Urology
    Steven A. Kaplan, Michael A. Volpe, Alexis E. Te
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    TLDR Finasteride improves chronic pelvic pain, saw palmetto doesn't.
    The study aimed to compare the effectiveness of saw palmetto and finasteride in treating chronic nonbacterial prostatitis/chronic pelvic pain syndrome. A total of 64 men were randomized to either finasteride or saw palmetto for 1 year. The study found that patients treated with finasteride had significant and durable improvement in all various parameters except voiding, while saw palmetto had no appreciable long-term improvement. Adverse events included headache in the saw palmetto group and decreased libido in the finasteride group. Further studies are warranted to ascertain the mechanism and reproducibility of these effects in a placebo-controlled trial.
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