A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration
January 2018
in “
Stem Cells International
”
TLDR Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
In the 2018 study, researchers found that conditioned media from deer antlerogenic mesenchymal stem cells (DaMSC-CM) could promote tissue regeneration, including hair regeneration, more effectively than media from adipose tissue-derived stem cells. The DaMSC-CM contained novel round vesicles, approximately 120 nm in diameter, which could regulate gene expression related to tissue renewal, such as Wnt-3a, Wnt-10b, and LEF-1. These findings suggest that DaMSC-CM and its secretory vesicles could have therapeutic applications for tissue regeneration. The study focused on cellular and molecular mechanisms and did not involve human subjects.
View this study on hindawi.com →
Cited in this study
5 / NoResultsresearch Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Wnt signaling induces epithelial differentiation during cutaneous wound healing
Wnt signaling is crucial for skin wound healing and reducing scars.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration
Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
research Biological characterization of cultured dermal papilla cells and hair follicle regeneration in vitro and in vivo
Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
Related
2 / NoResultsresearch Temporal-Spatial Activation of Wnt-Signaling Within Type 1 and Type 2 Immunity During Wound Healing
Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.