Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype

Low ferritin levels may contribute to hair loss, and raising ferritin above 40 or 70 ng/mL might help with hair regrowth. Some users also consider zinc deficiency and absorption issues as potential factors.

High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

The user is experiencing significant hair shedding and suspects it may be due to low serum ferritin levels rather than worsening androgenetic alopecia. They have resumed iron supplementation and are seeking additional solutions to address the shedding.

Dutasteride may affect testosterone levels, leading to high ferritin and iron levels, which can cause hair loss. High ferritin might be linked to past heavy drinking or hemochromatosis.

Low ferritin can contribute to hair loss despite normal iron levels, and supplementing iron may help improve hair regrowth when using finasteride. Minoxidil might also aid in recovery, and optimal ferritin levels for hair growth are suggested to be 100+ ng/ml.

Iron supplementation may be more effective than Minoxidil for hair loss. Checking ferritin levels is important, as both low and high levels can affect health.