Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management

May 2011 in “ Journal of Pediatric and Adolescent Gynecology ”

Selma F. Witchel, Ricardo Azziz

Congenital Adrenal Hyperplasia CYP21A2 gene androgen excess hirsutism acne alopecia anovulation menstrual dysfunction 17-OHP concentrations ACTH stimulation tests CAH hair loss excess androgens hair thinning irregular periods

Studysummary This review covers the pathophysiology, diagnosis, and treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency and reports no new findings.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on jpagonline.org →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

research Congenital Adrenal Hyperplasia: A Detailed Review of 21-Hydroxylase Deficiency

16 citations , September 2008 in “Dermatologic Therapy”

This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.

A Prospective Study of the Prevalence of Nonclassical Congenital Adrenal Hyperplasia Among Women Presenting with Hyperandrogenic Symptoms and Signs

research A Prospective Study of the Prevalence of Nonclassical Congenital Adrenal Hyperplasia Among Women Presenting with Hyperandrogenic Symptoms and Signs

150 citations , November 2007 in “The Journal of Clinical Endocrinology and Metabolism”

This study determined that nonclassical congenital adrenal hyperplasia has a 2.2% prevalence among hyperandrogenic women in Spain, with basal serum 17-hydroxyprogesterone showing excellent diagnostic performance.

research Screening for 21-Hydroxylase-Deficient Nonclassic Adrenal Hyperplasia Among Hyperandrogenic Women: A Prospective Study

216 citations , November 1999 in “Fertility and Sterility”

This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.

research Untreated Congenital Adrenal Hyperplasia Presenting with Severe Androgenic Alopecia

6 citations , April 1993 in “Journal of the Royal Society of Medicine”

Untreated Congenital Adrenal Hyperplasia can cause severe hair loss due to high androgen levels.