Co-Occurrence of Progressive Hemifacial Atrophy Due to Morphea With Homolateral Segmental Vitiligo: A Case Report

    April 2021 in “ Authorea (Authorea)
    Pukar Chapagain, Sudha Agrawal
    Studysummary In this case report, a woman with segmental vitiligo and hemifacial atrophy showed signs of stabilization after treatment with chloroquine and betamethasone pulse, suggesting a common underlying cause for these dermatoses.
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    This case report described a 20-year-old female with simultaneous Progressive Hemifacial Atrophy due to Morphea and homolateral segmental Vitiligo, which began at age 7. The conditions progressed rapidly before stabilizing, with depigmented macules and leukotrichia on the right forehead and upper eyelid, and a hyperpigmented, atrophied plaque on the right chin. Laboratory tests were normal, and a skin biopsy confirmed Morphea. Treatment with topical and oral medications halted disease progression, and the condition remained static for 9 years. The co-occurrence of these conditions suggested a possible relationship, though the exact pathogenesis remained unclear.
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