Metabolomic And Lipidomic Atlas Of Human Hair Across Its Length

    November 2025 in “ Communications Biology ”
    Maria van de Lavoir, Yuanye Chi, Ting Zeng, Rani Robeyns, María del Mar Delgado‐Povedano, L. Jacobs, Celine Gys, Hugo Neels, Shuzhao Li, Alexander L.N. van Nuijs, Adrian Covaci
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    Studysummary The researchers reported creating a Human Hair Atlas that maps over 1200 molecular species in hair, revealing up to 50% variation in metabolite and lipid levels along the hair's length, and identified 122 exposome-related compounds from personal care products.
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    The study presents a comprehensive metabolome and lipidome atlas of human hair, mapping over 1200 unique molecular species and highlighting significant longitudinal variations in metabolite and lipid levels, which can vary by up to 50% along the hair's length. The research identifies 122 exposome-related compounds, mainly from personal care products, aiding in biological interpretation. This publicly accessible Human Hair Atlas serves as a valuable resource for advancing research in hair metabolomics, lipidomics, and exposomics, and exploring hair's potential as a complementary matrix in clinical studies.
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