Therapeutic Efficacy of Platelet-Rich Plasma Combining with Microneedling and Topical Minoxidil in Refractory Severe Androgenic Alopecia

Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

Microneedling with topical minoxidil is effective for hair regrowth, especially with finasteride. Users report fewer side effects compared to oral minoxidil.

A physician experienced hair thickening and new growth using microneedling and minoxidil, but stopped using topical finasteride due to side effects like reduced libido and erectile dysfunction. The physician plans to continue with microneedling and minoxidil, considering finasteride nonessential for cosmetic purposes.

The user is experiencing hair regrowth using daily 5% minoxidil and weekly microneedling, and plans to add finasteride soon. They are considering the effectiveness of once-daily minoxidil and adjusting microneedling needle size.

A user reported noticeable hair regrowth after using 5% topical minoxidil daily and microneedling weekly since mid-January. They previously used dutasteride for four years with minimal effect.

Microneedling combined with minoxidil and finasteride improves hair growth in androgenetic alopecia, with effectiveness varying by severity. The study was retracted due to concerns about validity and potential AI-generated content.