Whole Neonatal Cochlear Explants as an In Vitro Model

July 2023 in “ Journal of visualized experiments ”

Soledad Levano, Yu Lei, Maurizio Cortada, Daniel Bodmer

neonatal cochlear explants hair cells spiral ganglion neuron cells supporting cells cochlea ototoxic drugs ototoxic assessments drug response experiments

Studysummary This study presents an improved protocol for isolating and culturing whole neonatal cochlear explants, enabling detailed analysis of hair cells and spiral ganglion neuron cells while simplifying culture steps without sacrificing explant quality, and was successfully tested on mice and rat cochleas.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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