June 2021 in “Clinical neuropsychopharmacology and therapeutics” This paper reviews the hair color changes associated with valproic acid treatment, noting only a few reported instances of bleaching or darkening, and reports no new findings.
65 citations
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July 2013 in “International Clinical Psychopharmacology” This review provides an overview of the prevalence and management of side effects of mood-stabilizing drugs in bipolar disorder patients and reports no new clinical results.
9 citations
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August 2006 in “American Journal of Psychiatry” This case report suggests that lamotrigine treatment may be associated with hair loss as a rare side effect, based on the observation of hair regrowth after discontinuation of the drug in a single patient.
6 citations
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October 2013 in “Expert Review of Dermatology” This review explores how psychotropic medications can cause a range of skin reactions, from mild to life-threatening, and emphasizes the importance of monitoring for these adverse effects early in treatment.
August 2023 in “Journal of The American Academy of Dermatology” In this commentary, the authors highlighted that valproic acid, unlike lamotrigine, is notably associated with alopecia in various studies, with an incidence rate up to 12% and mechanisms involving telogen effluvium and hyperandrogenism contributing to hair loss in patients.