August 2026 in “Tropical Journal of Pharmaceutical and Life Sciences” This study highlights that insulin resistance is a key pathological feature for individuals with PCOS, particularly those with obesity, affecting the response of specialized cells and leading to increased inflammation, regardless of Body Mass Index differences within the PCOS population.
February 2023 in “Frontiers in Endocrinology” In this study, prenatal androgen exposure was linked to altered sexual behaviors in both male and female mice, with specific effects on mounting and lordosis behaviors.
223 citations
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June 2018 in “Human Reproduction Update” This study concluded that including ovarian morphology in the diagnosis significantly increases the estimated prevalence of PCOS, revealing substantial variability due to clinical criteria and diagnostic cut-offs.
December 2023 in “Frontiers in endocrinology” This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.