Quantitation of Human Mitochondrial DNA and Whole Mitochondrial Genomes Sequencing of Fingernail and Hair Shaft Samples

    February 2024 in “ Forensic Sciences Research
    Hui Li, Yu Cao, Fan Yang, Xiling Liu, Ruiyang Tao, Ruocheng Xia, Ruxin Zhu, Lei Jiang, Shiquan Liu, Chengtao Li
    Studysummary In this study, researchers found that massively parallel sequencing of mitochondrial DNA (mtDNA) can improve information recovery from forensic samples, with successful full region amplification possible from as few as 2,000 mtDNA copies, albeit with variability in heteroplasmy among hair samples from the same donor.
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