An Unusual Case of Myxedema Coma

October 2024 in “ Journal of the Endocrine Society ”

Nazmul Hasan, Daniel S. Yang, Thaer Othman, Jenny Dai-Ju

myxedema coma hair loss hypothermia TSH primary hypothyroidism anti-TPO antibodies atrophic thyroid lobes Dexamethasone Levothyroxine Synthroid thyroid hormone

Studysummary This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.

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