Polycystic Ovary Syndrome - Metformin Treatment in Pregnancy

January 2005 in “ Duo Research Archive (University of Oslo) ”

Eszter Vanky

metformin polycystic ovary syndrome PCOS androgen levels

Studysummary Metformin reduces pregnancy complications in women with PCOS.

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The document discussed the use of metformin in pregnant women with polycystic ovary syndrome (PCOS). It was found that metformin reduced pregnancy complications without affecting androgen levels. Additionally, the study explored the placental passage of metformin in women with PCOS. The research involved clinical, biochemical, and ultrasonographic assessments of Scandinavian women with PCOS.

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research What May Be the Markers of the Male Equivalent of Polycystic Ovary Syndrome?

39 citations , January 2004 in “Physiological Research”

In this study, researchers reported that about one-third of men with premature alopecia displayed hormonal shifts and higher insulin resistance, resembling the prevalence pattern of PCOS in women.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome

4809 citations , January 2004 in “Fertility and Sterility”

This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.

research Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia

84 citations , November 2003 in “European journal of endocrinology”

This study found that women with androgenic alopecia had a higher prevalence of polycystic ovarian morphology and higher androgen levels compared to controls, suggesting a strong association with PCO.

research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome

192 citations , September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

This study suggests that metformin may be more effective than Dianette in treating moderate to severe hirsutism in women with PCOS, while also reducing markers of insulin resistance.

research The Effect of Metformin on Hirsutism in Polycystic Ovary Syndrome

90 citations , August 2002 in “European journal of endocrinology”

This study found that metformin treatment significantly improved hair growth in women with PCOS and hirsutism compared to a placebo.

research Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis

430 citations , July 2002 in “Journal of Endocrinology”

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.

research A Prospective Study of the Prevalence of Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain

491 citations , July 2000 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that the prevalence of polycystic ovary syndrome was 6.5% in a minimally biased sample of Caucasian women from Spain.

research Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study

633 citations , September 1998 in “The Journal of Clinical Endocrinology and Metabolism”

This study observed that among a cohort of reproductive-aged women in the U.S., the prevalence of PCOS was about 4.0%, with no significant racial differences between White and Black women.