scutellaria baicalensis

This study found that Scutellaria baicalensis extract and its main component baicalin inhibited androgen activation signaling and promoted proliferation of human dermal papilla cells, suggesting potential use in treating androgen-associated disorders.

In this study, baicalin from Scutellaria baicalensis decreased androgen levels in both cells and PCOS model rats by inhibiting key gene expression, suggesting it may be a potential treatment for hyperandrogenism in PCOS.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This study found that while some extracts from DanGuiBoHyulTangGami-Bang showed potential in inhibiting 5-reductase type Ⅱ and had antioxidant activity, they were not effective in extending the hair growth period.

In a mouse study, topical application of certain herbal extract mixtures showed accelerated hair regrowth compared to controls, with noted increases in specific enzyme activities and growth factors that may aid alopecia treatment.

In this study, Scutellaria baicalensis was observed to reduce tissue damage and inhibit 5α-reductase expression in a rat model of benign prostatic hyperplasia.

This study found that ultrasonic (ethanol) extracts of Salvia miltiorrhiza bunge and Scutellaria baicalensis were most effective for cell proliferation, while ethanol and ultrasonic waves (water) methods had high antioxidant activity, suggesting their potential in functional cosmetics.

This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.

This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.

This systematic review found that mangkokan leaf formulations, especially ethosomal gel or phytosome lotion at 25% concentration, were most effective in stimulating hair growth and improving hair health through various biological mechanisms.

This study found that baicalin activates Wnt/ß-catenin signaling in human dermal papilla cells, increasing alkaline phosphatase expression, growth factor expression, and promoting hair growth in mice.

This study reported that baicalin activates the Wnt/β-catenin signaling pathway in mouse hair follicles, suggesting its potential as a topical treatment for hair loss.

This study analyzed the geometric and electronic properties of baicalin conformers, finding that BCLa2TT and BCLa1TT conformers exhibit high stability in aqueous solutions and are favorable for interactions with positively charged species.

In this study, combining Kuntai capsules with nilestriol tablets for three months was found to reduce symptoms of perimenopausal syndrome and improve reproductive hormone levels more effectively than nilestriol alone; however, the benefits did not persist significantly beyond three months.

This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.

This review reports that while ginseng's safety profile seems favorable, the evidence for its clinical efficacy remains limited due to generally poor study quality in the included Korean randomized trials.

This study found that baicalin delivery through polymeric nanocapsules significantly enhanced its anticancer activity in breast cancer cell lines MCF-7 and MDA-MB-231.

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.

This animal study found that Cinnamomi cortex water extract reduced prostate weight and improved histological changes in a benign prostatic hyperplasia model, suggesting potential as a treatment.