Rhizoma Drynariae

This study suggests that acetone extracts and certain fractions of Drynariae Rhizomas may support hair growth when applied topically in C57BL/6N mice models, indicating potential use for treating alopecia areata.

This study found that Polygonum multiflorum and Panax japonicum extracts could promote hair regrowth in mice, suggesting potential use as hair tonics.

This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.

In this study, the researchers explored the traditional Chinese medicine approach to treating seborrheic alopecia, emphasizing the interplay between zang-fu organs, qi, blood, and body fluids, and highlighted treatments focusing on wind, dampness, heat, blood stasis, and deficiency.

This review summarizes methods for creating alopecia areata animal models and reports no new results, emphasizing that improved evaluation and combined disease models are needed for future research.

This study used association rule mining and network analysis to identify frequently combined herb sets for treating alopecia from 56 articles, highlighting the potential of Polygonum multiflorum, Angelica sinensis, and Ligusticum chuanxiong in traditional medicine and suggesting further bioinformatics research to understand their efficacy.

In this study, researchers analyzed the waters of Ladakh's hotsprings, identifying 27 bioactive compounds with potential health benefits, but emphasize that further clinical trials are needed to confirm their therapeutic efficacy and safety.

This study documented the traditional medicinal uses of 60 plant species in Kolli Hills, India, highlighting their importance in the healthcare of the local tribal community.

This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.

In this clinical study, plum blossom needle acupuncture and qi-invigorating therapy were reported to be more effective than conventional Western medicine for treating seborrheic alopecia, as they improved hormone levels, reduced hair loss, and stimulated hair growth among the 87 patients observed.

This review discusses the potential of plant-derived nanovesicles as natural therapeutics and drug delivery platforms in cancer therapy, highlighting their versatility and promising applications, but reports no new clinical results.

This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.

In this study, Gagamyeonryunggobon-dan treatment improved hair regrowth in ICR mice, as evidenced by increased hair thickness, sebaceous gland development, capillary formation, and markers of hair follicle activation.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

This study found that Rhizoma Zingiberis Recens significantly activated hair growth in C57BL/6J mice by increasing melanin and promoting hair follicle growth.

This study suggests that red ginseng rhizome extracts, particularly ginsenoside Ro, may promote hair re-growth in an androgenetic alopecia model due to their inhibitory activity on testosterone 5α-reductase.

In this experimental study, researchers found that Notopterygii rhizoma et radix (Qiang Huo) significantly alleviated psoriasis symptoms in mice and cell models, primarily by modulating the PI3K/Akt/mTOR pathway, indicating potential as a multi-target alternative therapy for psoriasis treatment.

This study concluded that hair tonic formulated with galangal rhizome and Aloe vera extract was stable according to the Indonesian National Standard, showing consistent organoleptic, pH, and viscosity characteristics after stability testing.

This review highlights the traditional use and potential therapeutic activities of Asiasari Radix in drug discovery, but it reports no new clinical results.

This study identified seven potential enzyme inhibitors from a Polygonum cuspidatum extract using ultrafiltration combined with high-performance liquid chromatography. These compounds showed inhibitory activity against tyrosinase, α-glucosidase, and xanthine oxidase, with most discovered in this extract for the first time.