Lecithin
Research
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research Lecithin Organogels as a Potential Phospholipid-Structured System for Topical Drug Delivery: A Review
This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
research Transdermal Permeation of Tetracaine Hydrochloride by Lecithin Microemulsion: In Vivo
In this study, lecithin/n-propanol/isopropyl myristate/water/tetracaine hydrochloride microemulsion was found to be a safe carrier for transdermal drug delivery in animal models, with analgesic effects on Wistar rats.
research Novel Stain-Free Lecithinized Coal Tar Formulation For Psoriasis
This study found that a new lecithinized coal tar formulation did not stain different types of mammalian hair, suggesting it may be promising for treating scalp psoriasis without the drawback of staining.
research Preparation and In Vivo Evaluation of Lecithin-Based Microparticles for Topical Delivery of Minoxidil
In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.
research Rheological Properties and Composition Affecting the Skin Permeation of a Model of a Hydrophilic Drug in Lecithin Reverse Wormlike Micelles
This study found that combining lecithin reverse wormlike micelles with isopropyl myristate enhanced the skin permeability of a model hydrophilic drug, facilitated by interactions with sebum in hair follicles.
research Boosting Hair Growth Through Follicular Delivery of Melatonin Through Lecithin-Enhanced Pickering Emulsion Stabilized by Chitosan-Dextran Nanoparticles in Testosterone Induced Androgenic Alopecia Rat Model
In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.
research PLGA–Soya Lecithin Based Hybrid Nanocomposite for Targeted Topical Delivery of Resveratrol in Psoriasis Management
This study developed a nanocarrier-based gel to enhance the delivery and effectiveness of resveratrol in treating psoriasis. In a mouse model, the gel improved skin penetration and retention, showed notable anti-psoriatic effects, and was deemed safe and biocompatible.
research Fully Natural Lecithin Encapsulated Nano-Resveratrol for Anti-Cancer Therapy
This study developed a fully natural resveratrol nanoparticle system using lecithin, showing potent anti-cancer activity in vitro and increased tumoral uptake in vivo on breast cancer models.
research The Protoporphyrin IX Dimethyl Ester Incorporated Soy Lecithin for Photoinactivation of Fluconazole-Resistant Candida Albicans
research Simultaneous Estimation of Minoxidil and Finasteride by RP-HPLC in Presence of Soy Lecithin Excipient in the Lotion Dosage Form
research Potential Antioxidant and Wound Healing Effect of Nano-Liposol with High Loading Amount of Astaxanthin
Nano-liposol with astaxanthin may improve antioxidant and wound healing effects.
research Microemulsions as Solubilizers and Penetration Enhancers for Minoxidil Release from Gels
This study found that minoxidil solubilized in gelatin-containing microemulsions resulted in over 5% of the drug remaining in porcine skin, significantly more than the reference gel.
research Complex Nanoemulsion for Vitamin Delivery: Droplet Organization and Interaction with Skin Membranes
This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.
research Phosphatides in Mouse Epidermis Undergoing Normal and Abnormal Growth Changes
This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.
research Hair Removal and Bioavailability of Chemicals: Effect of Physicochemical Properties of Drugs and Surfactants on Skin Permeation Ex Vivo
Hair removal methods damage the skin barrier and affect substance penetration.
research Oxidative Stress and Antioxidant Markers in Patients with Alopecia Areata: A Comparative Cross-Sectional Study
This study found that patients with alopecia areata had higher levels of oxidative stress markers and lower antioxidant enzyme activity compared to healthy controls.
research Effect of Liposomes Containing Antioxidant, Phospholipid, and Amino Acid on Skin Regeneration After Chemical Burn
Flamena, a liposomal mix, helps skin heal better after a chemical burn.
research Pufa-Rich Oil Supplement Improves Hair Condition Of Cats And Dogs
This study found that supplementing cat and dog food with PUFA-rich oil improved hair flexibility, brightness, and skin condition, though it also increased serum triglyceride levels, suggesting careful consideration of dosage and fatty acid composition is warranted.
research Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia
This study developed a quercetin-encapsulated and polydopamine-integrated nanosystem that reshapes the perifollicular microenvironment, showing potential for rescuing hair follicle viability and regenerating hair follicles in androgenic alopecia by scavenging reactive oxygen species and promoting angiogenesis.
research Podophyllotoxin-Loaded Solid Lipid Nanoparticles for Epidermal Targeting
This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.