Lauric acid
Research
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research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery
This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
research Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression
This study found that sebum free fatty acids may enhance the antibacterial defense of human sebaceous glands by upregulating the expression of the antimicrobial peptide hBD-2, potentially aiding in acne treatment.
research In Silico Analysis of Ethyl Acetate Bruguiera Gymnorhiza Leaf Extracts as an Anti-Inflammatory Agent
In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.
research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
This review discusses plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, as potential alternatives to 5-alpha-reductase inhibitors for prostate cancer treatment, highlighting their promising anti-cancer properties and potentially fewer side effects compared to conventional drugs.
research Physicochemical and Rheological Characterizations of Cocos Nucifera L. and Elaeis Guineensis Jacq. (Arecaceae) Oils for Black Hair Shampoo Formulation
This study evaluated coconut and palm kernel oils for their potential use in shampoos for black hair, finding they are rich in beneficial fatty acids and could serve as active ingredients due to their physicochemical and rheological properties.
research Test the Growth Process of Hair Follicles by Administering Coconut and Candlenut Oil to the Entire Back of White Rats (Rattus Norvegicus) of the Wistar Strain
This study found that a mixture of 80% coconut oil and 20% candlenut oil effectively stimulated hair development in Wistar rats, which may be attributed to the high lauric acid content in coconut oil.
research Quality Assessment of Herbal Medicinal Products in Benign Prostate Hypertrophy: Chemical Markers and Fingerprint Analysis
In this study, GC/MS analysis revealed variability in the quality of Syrian herbal formulations for BPH, with variations in tocopherol content, presence of parabens, and shortages of certain phytosterols.
research Prospective Efficacy and Safety Study of an Innovative Kerascalp Hair Growth Serum in Mild-to-Moderate Alopecia in India: Regrowth Study
In this open-label study, the researchers observed that using Kerascalp hair serum daily for 90 days improved hair thickness, density, and strength while reducing hair loss in subjects with mild to moderate androgenetic alopecia, with benefits persisting even after discontinuation.
research The Potential of Moringa (Moringa Oleifera Lamk) Seed Oil as Anti-Alopecia
This review examined moringa seed oil's potential to combat alopecia, reporting that its phytosterol and fatty acid compounds may block dihydrotestosterone formation and support healthy hair growth.
research Enriched And Enhanced Virgin Coconut Oil (2EVCO)
In this study, the application of Enriched and Enhanced Virgin Coconut Oil reportedly improved hair growth and reduced the appearance of scars in a teacher with cancer, suggesting benefits over typical post-chemotherapy recovery.
research Morpho-Anatomy, Chemical Variability, And Biological Activity Of The Fixed Oil From Seeds Of Apeiba Tibourbou Aubl. – Malvaceae
In this study, the fixed oil extracted from Apeiba tibourbou seeds showed potential analgesic and anti-inflammatory properties, with prominent constituents including omega-3 and omega-6 fatty acids.
research News in Brief
Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.
research Effect of Sodium Lauryl Sulfate Concentration Variation as Surfactant in Ethanol Extract Shampoo of Randu Leaves (Ceiba Pentandra Gaertn) on the Resulting Physical Properties
This study concluded that a shampoo with 10% sodium lauryl sulfate showed the best physical properties among the tested formulas, aligning closely with the Indonesian National Standard.
research Effect of Coconut Oil in the Management of Post-Denture Insertion Mucosal Changes: A Cross-Sectional Survey
In this study, Cocos nucifera (coconut) oil's antimicrobial properties showed effectiveness against Candida albicans and Streptococcus in an in vitro biofilm model, and its lauric acid content may reduce plaque adhesion and support oral health.
research Morphological and Biochemical Investigations of Hair in Disturbed Amino Acid Metabolism
Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.
research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
This study identified that the enzyme CYP2B12 is skin-specific and likely plays a role in the metabolism of arachidonic acid, a key component in lipid signaling within sebaceous glands.
research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery
This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.
research Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes
This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.
research Experimental and Clinical Pharmacology of Ziziphus Jujuba Mills
This review reports on the traditional and ethnopharmacological uses of Ziziphus jujuba Mills, noting its increasing global popularity for treating various ailments, but highlights that its acceptance into the European Pharmacopoeia remains unresolved due to scientific and regulatory challenges.
research A Systematic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia
This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.