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research Intra-Host SARS-CoV-2 Single-Nucleotide Variants Emerged During the Early Stage of COVID-19 Pandemic Forecast Population Fixing Mutations
This article discusses intra-host single-nucleotide variants in SARS-CoV-2, highlighting their potential to inform on virus strain diversity, immune escape, and drug design, but it reports no new clinical results.
research Intra-Ovarian Doppler Artery Indices Values in Cases with Polycystic Ovarian Syndrome: A Case Control Study
This study observed that women with PCOS have lower resistive and pulsatility index values in ovarian stromal arteries compared to normal women, indicating Doppler ultrasonography as an effective diagnostic tool for PCOS-related hemodynamic changes.
research Intra-Individual Comparative Study of Methotrexate Versus Triamcinolone Acetonide Delivered via Microneedling for Recalcitrant Alopecia Areata
This study found that while both microneedling-assisted methotrexate and triamcinolone acetonide treatments led to improvements in recalcitrant alopecia areata, methotrexate-treated areas had significantly better outcomes in terms of SALT score reduction, patient satisfaction, and relapse rates, suggesting its superior short-term efficacy.
research Severe Lichen Planus Pigmentosus Inversus in an Elderly Female Following Intra-Articular Injections of Homeopathic Substances
In this case study, an 80-year-old woman developed lichen planus pigmentosus inversus after receiving multiple intra-articular injections of a homeopathic preparation, suggesting a possible link, though causality remains speculative.
research Ciliary Madarosis Secondary to Intra-Arterial Chemotherapy for Retinoblastoma Treatment
This article discusses ciliary madarosis as a transient condition secondary to IAC, emphasizing the value of physical and trichoscopic evaluations for diagnosis and prognosis; it does not report new clinical results.
research Stability Study of Finasteride: Stability-Indicating LC Method, In Silico and LC-ESI-MS Analysis of Major Degradation Product, and an In Vitro Biological Safety Study
In this study, researchers found that finasteride undergoes second-order alkaline degradation kinetics and that its degraded form negatively impacts cell proliferation, highlighting the need for careful handling in pharmaceutical manufacturing and storage.
research In Vivo Anti-Trichophyton Activities of Seed Oil Obtained from Caragana Korshinskii Kom.
This study found that seed oil of Caragana korshinskii demonstrated high antifungal efficacy against Trichophyton mentagrophytes in an in vivo guinea pig model of dermatophytosis.
research Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration
This review discusses strategies to regenerate human hair follicles using stem cells and reports no new experimental results; the authors note existing challenges and the potential of hiPSCs for future applications.
research A Comparison of Intralesional Triamcinolone Hexacetonide and Triamcinolone Acetonide in Alopecia Areata
This study found that both intralesional triamcinolone acetonide and triamcinolone hexacetonide promote continuous hair growth in alopecia areata, with effects lasting at least 9 months after a single injection.
research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients
This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels
This study suggests that hepatocellular carcinoma in cirrhotic men is associated with altered sex-steroid metabolism, indicated by lower testosterone and 5 alpha-dihydrotestosterone levels compared to cirrhosis alone.
research Effect of Intra-Articular Platelet Rich Plasma Injection on Knee Osteoarthritis Patients
This study found that intra-articular PRP injections led to significant clinical improvements in patients with knee osteoarthritis.
research Comparison of Intra-Operative Blood Loss in Patients Undergoing Mono-Polar TURP With and Without Pre-Operative 2 Weeks Use of Finasteride
This study found that administering Finasteride for two weeks before surgery significantly reduced intraoperative blood loss in patients undergoing monopolar TURP, with the interventional group experiencing less mean blood loss and shorter operative times compared to the control group.
research Comparison of Efficacy of Intralesional Injections of Platelet-Rich Plasma Therapy Versus Intralesional Triamcinolone Acetonide in the Treatment of Patients With Alopecia Areata at a Tertiary Care Hospital
PRP injections are more effective than triamcinolone for treating alopecia areata.
research Comparison of Intra-Lesional Methotrexate and Intra-Lesional Triamcinolone Acetonide in the Treatment of Localized Alopecia Areata
This comparative clinical study found no statistically significant difference in the remission and recurrence rates between intralesional triamcinolone acetonide and methotrexate for treating localized alopecia areata, suggesting similar efficacy between the two treatments.
research Risk Decrease of Intra-Operative Bleeding During TURP with the Uptake of Finasteride: Evaluation of VEGF and CD34
Finasteride reduces bleeding risk during prostate surgery.
research Phytochemical and Infrared Radiation Test of Mangkokan Leaf (Nothophanax Scutellarium Merr.)
This study identified that Mangkokan leaf extracts contain active compounds such as alkaloids, flavonoids, steroids, tannins, phenols, and saponins, using different solvents and FTIR analysis.
research Step-Down Approach to Concentration of Intralesional Triamcinolone Acetonide in Treatment of Scalp Patchy Alopecia Areata: Insights from an Open-Label Randomized Trial
Using a higher concentration of triamcinolone acetonide leads to faster hair regrowth in scalp patchy alopecia areata.
research Segmental Analysis of Human Hair Reveals Intra-Annual Variation in 25(OH)D3 Concentrations in Modern and Archaeological Individuals
This study explored 25-hydroxyvitamin D3 levels in hair samples from participants in Aberdeen and suggested potential links between hair vitamin D levels, seasonal UVB exposure, and marine diet in both modern and archaeological contexts.
research Do Autologous Platelet Concentrates (APCs) Have a Role in Intra-Oral Bone Regeneration? A Critical Review of Clinical Guidelines on Decision-Making Process
This narrative review concluded that autologous platelet concentrates, particularly L-PRF, effectively enhance bone and soft tissue healing in periodontal regenerative procedures, with L-PRF demonstrating the most convincing results and ease of use.