ceramide
Research
20 / 832 resultsresearch LC/MS Analysis of Stratum Corneum Lipids: Ceramide Profiling and Discovery
This study reports a novel LC/MS method that separates and analyzes all known ceramide subclasses in human stratum corneum, identifying a new subclass, CER [EOdS], with minimal sample preparation.
research Ceramide Synthase 4 Deficiency in Mice Causes Lipid Alterations in Sebum and Results in Alopecia
This study found that mice deficient in ceramide synthase 4 showed altered sebum composition and progressive hair loss due to obstructed hair canals.
research Ceramide Synthase 4 Regulates Stem Cell Homeostasis And Hair Follicle Cycling
This study found that inactivating CerS4 in mice led to hair follicle stem cell exhaustion and hair loss, indicating its role in regulating hair regeneration through ceramide composition and signaling pathways.
research Ceramide Binding to African-American Hair Fiber Correlates with Resistance to Hair Breakage
This study found that a ceramide derived from sphinganine can bind to African–American hair, reducing breakage when applied in a shampoo after relaxing treatments.
research Alkaline Ceramidase 1 Is Essential for Mammalian Skin Homeostasis and Regulating Whole-Body Energy Expenditure
This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.
research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
This study found that loss of the ACER1 gene in mice led to increased ceramide levels and progressive hair loss, highlighting ACER1's role in maintaining hair follicle stem cell homeostasis.
research Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis
Ceramide Synthase 4 is crucial for healthy skin barrier function.
research Ceramide: A New Approach to Hair Protection and Conditioning
This study reports on the vulnerability of hair's structural lipids to physical and chemical damage and describes properties of hair treated with a synthesized ceramide derivative.
research Promotion of Hair Growth by Newly Synthesized Ceramide Mimetic Compound
This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.
research Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
This study suggests that synthetic ceramides may promote hair growth by inducing proliferation of human dermal papilla cells through modulation of Wnt/β-catenin and BMP2/4 signaling pathways.
research New Fluorogenic Probes for Neutral and Alkaline Ceramidases
This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.
research Damaged Hair Retrieval with Ceramide-Rich Liposomes
In this study, the use of internal wool lipid liposomes was shown to improve the lipid composition and increase the resistance to breaking in both untreated and chemically treated hair fibers.
research Evaluation of Methotrexate-Loaded Surfactants, Ceramides, and Cholesterol-Based Lamellar Phases as a Topical Treatment for Psoriasis
In this study, two methotrexate-loaded liquid crystal formulations for topical application showed immunomodulatory effects and induced skin changes in mice with imiquimod-induced psoriasis.
research Skin Barrier, Phenotypic and Genotypic Characterization of Autosomal Recessive Ichthyosis in TGM1-Deficient Jack Russell Terriers and Response to Topical Ceramide
This study reported that topical ω‐0‐acylceramide improved skin barrier function in Jack Russell Terriers with TGM1-deficient autosomal recessive congenital ichthyosis, normalizing skin pH and reducing transepidermal water loss.
research Stress-Induced Senescence of Dermal Papilla Cells Restored by Synthesized Ceramide
This study suggests that ceramide may help maintain hair follicles under stress by modulating growth factor pathways in senescence-induced dermal papilla cells.
research Stress-Induced Senescence of Dermal Papilla Cells Restored by Synthesized Ceramide
Ceramide may help delay hair aging by restoring stressed hair cells.
research Role of Alkaline Ceramidase 1 in Regulating Epidermal Homeostasis and Tumorigenesis
This study found that the enzyme Acer1 plays a crucial role in skin health and tumor prevention by regulating ceramide metabolism in mice.
research Case-Control Study: The Effects of Synthetic Ceramide on Dandruff, Erythema, Sebum Secretion, and Water Loss of Scalp
This study found that synthetic ceramide shampoo improved dandruff and erythema while reducing water loss when compared to control in a group of 20 subjects over four weeks.
research Ceramide Synthase 4 Controls Epidermal Lipid Composition and Barrier Function
This study found that inactivating CerS4 in mouse epidermis disrupts lipid homeostasis and is crucial for maintaining, but not forming, the skin barrier.
research The Effect of Ceramide-Based Essence Cream for the Damaged Hair Shaft
This study found that ceramide-based essence cream, particularly those with stearyl and stearyl-cholesterol, improved the ultrastructure of damaged hair cuticles.