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research Anogenital Distance as a Biomarker for Incomplete Masculinization: Molecular Mechanisms in the Perineum
A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
research Mixture Effects of Endocrine Disrupting Compounds In Vitro
Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
research Identification and Molecular Characterization of a New Ovarian Cancer Susceptibility Locus at 17q21.31
A new genetic region, 17q21.31, is linked to higher ovarian cancer risk.
research Characterization of the In Vitro, Ex Vivo, and In Vivo Efficacy of the Antimicrobial Peptide DPK-060 for Topical Treatment
DPK-060 in poloxamer gel effectively treats skin infections, but nanocarriers don't enhance its efficacy.
research Erosive Pustular Dermatosis of the Scalp: Clinical, Trichoscopic, and Histopathologic Features of 20 Cases
The conclusion is that high-potency steroids or tacrolimus are effective treatments for erosive pustular dermatosis of the scalp.
research Exploiting Unique Features of Microneedles to Modulate Immunity
Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
research Alkaline Ceramidase 1 Is Essential for Mammalian Skin Homeostasis and Regulating Whole-Body Energy Expenditure
Alkaline ceramidase 1 is crucial for healthy skin and energy balance.
research New Onset of Alopecia Areata in a Patient with SARS-CoV-2 Infection: Possible Pathogenetic Correlations
COVID-19 infection may trigger alopecia areata in some patients.
research Metabolic Syndrome Prevalence in Psoriasis
People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.
research Telogen Effluvium After SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms
COVID-19 may cause early hair loss similar to classic temporary hair loss, with further research needed.
research 5-Alpha-Reductase 2 Inhibition Impairs Brain Defeminization of Male Rats: Reproductive Aspects
5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
research Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
research Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice
15d‐PGJ2 cream protects against UVB-induced skin damage in mice.
research Factors Regulating Quiescent Stem Cells: Insights from the Intestine and Other Self-Renewing Tissues
The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
research Southern African HIV Clinicians Society Gender-Affirming Healthcare Guideline for South Africa
The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
research Erosive Pustular Dermatosis of the Scalp: A Clinicopathologic Study of Fifty Cases
The conclusion is that Erosive Pustular Dermatosis of the Scalp is a rare condition best treated with strong topical steroids and sometimes systemic treatment.
research Complete Pseudo-Anodontia in an Adult Woman with Pseudo-Hypoparathyroidism Type 1a: A New Additional Nonclassical Feature?
A woman with a rare hormone resistance condition also had missing teeth and hair loss, which might be new symptoms of her genetic disorder.
research Compounded Topical Preparations in Plaque Psoriasis: Still a Place for It in 2018?
Compounded topical preparations should be used with caution for severe psoriasis and generally come after systemic treatments.
research Investigating the Role of Obesity, Circadian Disturbances, and Lifestyle Factors in People with Schizophrenia and Bipolar Disorder: Study Protocol for the SOMBER Trial
The trial aims to understand how obesity and lifestyle affect circadian rhythms in people with schizophrenia and bipolar disorder.
research Dermatology Resident Comfort Level Treating Hair Conditions Related to Patients with Skin of Color
Dermatology residents need better training to treat hair conditions in patients with skin of color.