Finasteride and minoxidil 1.5 years, sudden shed What should I do?
    Finasteride/Dutasteride 4/18/2023

    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Finasteride (oral) 1mg 1x daily 1.5 years
    💧 Minoxidil (topical) 1.5 years
    the tone is 😞 negative.

    Other terms

    Hair loss discussion involved Finasteride, Minoxidil, and RU58841. User experienced sudden shedding after 1.5 years of Finasteride and Minoxidil use, seeking advice.
    View this post in the Community →

    Similar Community Posts Join

    6 / 6 results

      community Which 2026 hair‑loss treatments have the strongest evidence so far? (minoxidil/finasteride vs. clascoterone, PP405, Re:You’s NV‑623/624, AMP‑303, RU58841)

       44 upvotes 2 months ago
      Minoxidil and finasteride are the only FDA-approved treatments for androgenetic alopecia, while newer treatments like clascoterone, PP405, NV-623/624, AMP-303, and RU58841 are still experimental with varying levels of evidence. Clascoterone shows the most promise due to strong human data, while AMP-303 has notable early human trial results; RU58841 lacks human data and remains experimental.

      community 1year Fin -> 1 year DUT + oral Minox; No results :(

      in Finasteride/Dutasteride  41 upvotes 2 months ago
      The user tried finasteride, dutasteride, and oral minoxidil for hair loss with no success and was diagnosed with androgenetic alopecia. They are considering increasing dosages and trying other treatments like RU58841, GHK-CU, and clascoterone, while seeking further medical opinions.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 4 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Is this retrograde alopecia ??

      in Chat  24 upvotes 1 year ago
      The conversation discusses hair thinning and treatments like finasteride, dutasteride, oral and topical minoxidil, and RU58841. Users share experiences with retrograde alopecia, hair transplants, and stress-related hair loss, while also considering thyroid issues and other potential causes.

      community any news about DUPA (Diffuse unpatterned alopecia)?

       8 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

    Related Research

    6 / 6 results
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      research CLINICAL UPDATES IN HAIR

      19 citations , January 1997 in “Dermatologic Clinics”
      This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.
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      Hair Growth and Rejuvenation: An Overview

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      This review discusses recent advancements in hair rejuvenation strategies and assesses the potential of herbal drugs as safer alternatives, but reports no new clinical results.
      Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      August 2025 in “Drug Design Development and Therapy”
      This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.